If anyone is interested, here is the process, Thx Dr Dan:
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ARDS is a syndrome with many precipitating factors. SARS and MERs were specific viral infections, like Covid 19, that cause ARDS. It is common in drug overdose either from pulmonary edema or aspiration pneumonia, happens commonly after sepsis.
Management- aside from any specific anti-microbial treatment needed, is usually sedation/paralysis with aggressive ventilator and oxygen support as well as positive end expiration pressure to prop up the lungs. Oxygen only makes matters worse at high concentrations as it is directly toxic to the lung. If you survive it takes weeks of ventilator management to get the lungs healed.
High resistance in the lung impedes blood flow and creates secondary cardiovascular insufficiency. The lung mechanisms regulating blood flow to match air flow become dysfunctional and even with oxygen supplementation it can be impossible to get adequate oxygenation due to this localized V/Q mismatch. Many are so unstable you can’t even turn them or move them without catastrophic hypotension."
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Makes sense now how they are able to treat 2 patients with 1 ventilator, sedation/paralysis is part of the treatment.
This is a really nasty self perpetuating process and will tie up a ventilator for weeks.
Friend at Phillips told me they are ramping up ventilator production working day and night. As is Siemens, Puritan Bennet, and Bear. The greatest fear is simply running out of medical supplies since countries who make things like masks aren't sending them out (China) but keeping them. Tubing sets, IV lines, PPE, drugs, etc. And of course running out of medical staff.
.................................................. .................................................. ................
ARDS is a syndrome with many precipitating factors. SARS and MERs were specific viral infections, like Covid 19, that cause ARDS. It is common in drug overdose either from pulmonary edema or aspiration pneumonia, happens commonly after sepsis.
Management- aside from any specific anti-microbial treatment needed, is usually sedation/paralysis with aggressive ventilator and oxygen support as well as positive end expiration pressure to prop up the lungs. Oxygen only makes matters worse at high concentrations as it is directly toxic to the lung. If you survive it takes weeks of ventilator management to get the lungs healed.
High resistance in the lung impedes blood flow and creates secondary cardiovascular insufficiency. The lung mechanisms regulating blood flow to match air flow become dysfunctional and even with oxygen supplementation it can be impossible to get adequate oxygenation due to this localized V/Q mismatch. Many are so unstable you can’t even turn them or move them without catastrophic hypotension."
.................................................. .................................................. .......................
Makes sense now how they are able to treat 2 patients with 1 ventilator, sedation/paralysis is part of the treatment.
This is a really nasty self perpetuating process and will tie up a ventilator for weeks.
Friend at Phillips told me they are ramping up ventilator production working day and night. As is Siemens, Puritan Bennet, and Bear. The greatest fear is simply running out of medical supplies since countries who make things like masks aren't sending them out (China) but keeping them. Tubing sets, IV lines, PPE, drugs, etc. And of course running out of medical staff.
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